ISO 19238:2023
p
ISO 19238:2023
82295
недоступно на русском языке

Текущий статус : Опубликовано

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Тезис

This document provides criteria for quality assurance and quality control, evaluation of the performance and the accreditation of biological dosimetry by cytogenetic service laboratories using the dicentric assay performed with manual scoring.

This document is applicable to

a)    the confidentiality of personal information, for the requestor and the service laboratory,

b)    the laboratory safety requirements,

c)    the calibration sources and calibration dose ranges useful for establishing the reference dose-response curves that contribute to the dose estimation from unstable chromosome aberration frequency and the detection limit,

d)    the scoring procedure for unstable chromosome aberrations used for biological dosimetry,

e)    the criteria for converting a measured aberration frequency into an estimate of absorbed dose,

f)     the reporting of results,

g)    the quality assurance and quality control, and

h)    informative annexes containing sample instructions for requestor (see Annex A), sample questionnaire (see Annex B), sample report (see Annex C), fitting of the low dose-response curve by the method of maximum likelihood and calculating the error of the dose estimate (see Annex D), odds ratio method for cases of suspected exposure to a low dose (see Annex E), a method for determining the decision threshold and detection limit (see Annex F) and sample data sheet for recording aberrations (see Annex G).

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Общая информация

  •  : Опубликовано
     : 2023-08
    : Опубликование международного стандарта [60.60]
  •  : 3
  • ISO/TC 85/SC 2
    13.280  17.240 
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